Polycan을 함유한 calcium gluconate 복합제의 치은건강 개선효과
Polycan-calcium gluconate complex improves gingival health
최연희, 김지혜, 김재영, 이영균, 양해영, 송근배,
소속 상세정보
최연희 ( Choi Youn-Hee ) - 경북대학교 치의학전문대학원 예방치과학교실
김지혜 ( Kim Ji-Hye ) - 경북대학교 치의학전문대학원 예방치과학교실
김재영 ( Kim Jae-Young ) - 경북대학교 치의학전문대학원 구강생화학교실
이영균 ( Lee Young-Kyun ) - 경북대학교 치의학전문대학원 구강생화학교실
양해영 ( Yang Hae-Young ) - 경북대학교 치의학전문대학원 예방치과학교실
송근배 ( Song Keun-Bae ) - 경북대학교 치의학전문대학원 예방치과학교실
KMID : 0355420130370040175
Abstract
Objectives: The aim of this study was to examine the effect of a Polycan-calcium gluconate complex on gingival health.
Methods: Forty-one subjects with mild periodontitis (≥40 years) were divided into two groups: the placebo and test product (Polycan-calcium gluconate complex twice a day for 4 weeks) groups. Oral examination was performed and gingival crevicular fluid (GCF) was collected from each subject at baseline and after 4 weeks. Interleukin (IL)-1βlevel in the GCF was determined using enzyme-linked immunosorbent assay.
Results: Pocket depth and plaque index were significantly decreased in the test group at 4 weeks. The level of IL-1β and plaque index of the treatment group was significantly lower than of the placebo group.
Conclusions: Based on the above results, Polycan-calcium gluconate complex may inhibit plaque accumulation in the mouth and may have a negative correlation with the level of inflammatory biomarkers. Consequently, gingival health was significantly improved by polycan-calcium gluconate complex.
키워드
β-glucan; Calcium gluconate; Gingival health; Polycan
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